Wed. Nov 6th, 2024

Product Name :
Anti-DPP4, Human antibody

Applications:
ELISA,Flow Cyt

Reactivity :
Human

Conjugate:
Unconjugated

Advantages :
High lot-to-lot consistencyIncreased sensitivity and higher affinityAnimal-free production

Description:
| Description: Anti-DPP4, Human antibody is designed for detecting human DPP4 specifically. Based on ELISA and/or FCM, Anti-DPP4, Human antibody reacts with human DPP4 specifically. | Immunogen: Recombinant human DPP4 | Host: Alpaca pacous | Isotype: Human IgG1 | Conjugate: Unconjugated | Specificity: Human DPP4 | Purity: Recombinant Expression and Affinity purified | Concentration: 1mg/ml | Formation: Liquid, 10mM PBS (pH 7.5), 0.05% sucrose, 0.1% trehalose, 0.01% proclin300, 50% Glycerol | Storage: Store at –20 °C, (Avoid freeze / thaw cycles) | Background:CD26 (dipeptidyl peptidase IV, DPP IV), adenosine deaminase (ADA) binding protein) is a homodimeric atypical serine protease belonging to the prolyl oligopeptidase family. CD26 is expressed on lymphocyte cells and is upregulated during T-cell activation. CD26 is also expressed on activated B cells and natural killer cells and abundantly on epithelia. CD26 is implicated in a variety of biological functions including T-cell activation, cell adhesion with extracellular matrix such as fibronectin or collagens, and in HIV infection. CD26 identical to adenosine deaminase complexing protein-2, and to the T-cell activation antigen CD26. Further, CD26 is an intrinsic membrane glycoprotein and a serine exopeptidase that cleaves X-proline dipeptides from the N-terminus of polypeptides.Briquilimab Alterations in CD26 peptidase activity are characteristic of malignant transformation, and the enzymatic activity increases dramatically with tumor grade and severity. CD26 is expressed in various blood cell types, but also in cells that are histogenetically related to activated fibroblasts. Alterations in CD26 density have been reported on circulating monocytes and CD4+ T cells during rheumatoid arthritis and systemic lupus erythematosus.

Description2 :
Anti-DPP4, Human antibody is designed for detecting human DPP4 specifically. Based on ELISA and/or FCM, Anti-DPP4, Human antibody reacts with human DPP4 specifically.

Immunogen:
Recombinant human DPP4

Host :
Alpaca pacous

Isotype:
Human IgG1

Purity :
Recombinant Expression and Affinity purified

Buffer :

Storage :
Store at –20 °C, (Avoid freeze / thaw cycles)

Function:
ELISA: 1:4,000-1:10000Flow Cytometry:1:200-1:1000Dilution factors are presented in the form of a range because the optimal dilution is a function of many factors, such as antigen density, permeability, etc.Chloramphenicol The actual dilution used must be determined empirically.PMID:24189672