Product Name :
Thiamet G
Synonym :
1,2-Dideoxy-2′-ethylamino-a-D-glucopyranoso-[2,1-d]-2′-thiazoline(3aR,5R,6S,7R,7aR)-2-(Ethylamino)-3 a,6,7,7a-tetrahydro-5-(hydroxy methyl)-5H-pyrano[3, 2-d]thiazole-6,7-diol
Chemical Name :
CAS NO.:
1009816-48-1
Molecular formula :
C9H16N2O4S
Molecular Weight:
248.3 g/mol
Classification :
MedChemExpress Products > Carbohydrates > Monosaccharides > Thiamet G
Description:
Inhibits β-N-acetylglucosaminidase, also known as O-GlcNAcase (OGA), which cleaves the O-linked glycans from glycoproteins. Interferes with O-GlcNAc cycling and leads to the accumulation of O-GlcNAcylated proteins. Thiamet G elicits neuroprotective effects by modulating microglia/macrophages and inhibiting hyperphosphorylation of the microtubule-associated protein tau in models of stroke and Alzheimer’s disease. Thiamet G also has implications on diabetes and cardiovascular pathologies.
Purity :
>98%
Specifications :
10 mM * 1 mL
Price.:
87
Price unit :
$
Inventory :
In stock
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