N sensitive and is only considered active under anaerobic conditions . The presence of genes predicted to encode PFL or genes that resemble the PDH-genes of other organisms does not…
Ather activation of the Gi pathway is mediated by secondary release of ADP, which acts on the Gi-coupled ADP receptor, P2Y12 . A common feature of PAR4 across species is…
Veniently used in clinical practice, especially in developing countries for differentiating significant fibrosis with mild fibrosis in patients with chronic hepatitis B. Liver stiffness is believed one of best non-invasive…
Metastatic tumors. To our knowledge, this is the first reported proteomic analysis by 2D-DIGE analysis of ascites from patients with intrinsic chemoresistant and chemosensitive ovarian cancer. Additionally, the results may…
Nockout (KO) zebrafish, which provided a new genetic model system to study FXS . However, research analyzing the phenotypic characteristics of fmr1 KO zebrafish in adulthood is sparse. In a…
Onents of the Wingless pathway, wingless and armadillo, for interactions with lqfR/Tel2. Wingless ligand binds its receptor Frizzled which results in accumulation in the nucleus of the transcriptional regulator Armadillo…
Larger in individuals with a history of illicit stimulant use than in non-drug users and cannabis users. The hyperechogenicity observed in stimulant users (0.27360.078 cm2) was comparable to older adults…
Er's recommendation. Real time PCR reaction mixtures have been described previously . Briefly, cDNA was synthesized by reverse transcription reaction using the First Strand cDNA synthesis kit (Invitrogen). Real-time PCR…
Erienced by residues in close spatial proximity to the site of the mutation; (b) mutation specific perturbations on interaction networks that involve the mutated site; (c) nearest neighbour effects experienced…
Myeloma RPMI-8226 cells. Cell uptake of 64Cu-CB-TE1A1P-LLP2A (0.1 nM), in human RPMI-8226 cells at 37uC in the absence (red bar) and presence (blue bar) of excess LLP2A (P,0.0001). doi:10.1371/journal.pone.0055841.g008 Figure…