He C. paliurus physically ideal. So the later elution of benzoic acid primarily depended on hydrophilia. Following the adsorption equilibrium, the ECM was desorbed with depended on hydrophilia. Following the adsorption equilibrium, the ECM was desorbed with depended on hydrophilia. After the adsorption equilibrium, the ECM was desorbed with 40 methanol remedy and benzoic acid with high purity of 82.22 was obtained. This 40 methanol resolution and benzoic acid with aaahighpurity of 82.22 was obtained. This 40 methanol resolution and benzoic acid with high purity of 82.22 was obtained. This method for the separation and purification of benzoic acid from C. paliurus extract was approach for the separation and purification of benzoic acid from C. paliurus extract was technique for the separation and purification of benzoic acid from C. paliurus extract was successfully established by ECM. The recovery of benzoic acid was a lot more than 80 . The effectively established by ECM. The recovery of benzoic acid was much more than 80 . The successfully established by ECM. The recovery of benzoic acid was more than 80 . The proposed method was reduced expense, nontoxic, higher efficiency, and procedurally straightforward. It proposed process was reduce expense, nontoxic, high efficiency, and isis procedurally basic. It proposed technique was lower cost, nontoxic, high efficiency, and is procedurally straightforward. Itbelieved that the positive aspects of on the proposed system will facilitateits application in isisis believed thatthe positive aspects with the proposed process will facilitate its application in believed that the advantages the proposed approach will facilitate its application in simultaneousseparation and purification of active elements which have related polarity, simultaneous separation and purification of active components that have equivalent polarity, simultaneous separation and purification of active elements which have equivalent polarity, different sizes of molecules, and are derived from the similar all-natural items. diverse sizes of molecules, and are derived from the identical natural products. various sizes of molecules, and are derived in the identical natural items.Supplementary Supplies: The following D-Fructose-6-phosphate disodium salt site material offered on the internet. Scheme S1: Chromatogram of is out there on the internet at https://www.mdpi.com/ Supplementary Material: The following material isis available on the net. Scheme S1: Chromatogram of Supplementary Material: The following material 11-Aminoundecanoic acid PROTAC Linkers article/10.3390/chemistry3040081/s1. Scheme S1: Chromatogram of benzoic acid common. benzoic acid normal. benzoic acid typical. Author Contributions: Conceptualization, Y.Z.; Investigation, X.Z. and M.L.; Sources, L.A. and L.C.; Software program, L.S.; Supervision, Q.L. and P.Z.; Visualization, L.X.; Writing–original draft, L.Z. All authors have study and agreed for the published version on the manuscript.Chemistry 2021,Funding: This analysis received no external funding or This study was funded by [ the Fundamental Analysis Funds for the Central Universities of northwest Minzu university] grant number [31920180003, Yxm2019136, Yxm2020119, 31920190017, and 31920190018] And also the APC was funded by [Ya-Min Zhao]. Institutional Assessment Board Statement: Not applicable. Informed Consent Statement: Not applicable. Data Availability Statement: Not applicable. Acknowledgments: This perform was supported by the Fundamental Study Funds for the Central Universities of northwest Minzu university (31920180003, Yxm2019136, Yxm2020119, 31920190017, and 31920190018). Conflict.