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The wondering and dynamics location for medicinal chemistry was explored by the carbohydrates compounds and their esters applied and authorized drugs against antibacterial, antifungal, antitumor, antiviral, anti-diabetic, anti-inflammatory, antineoplastic and antiprotozoal of human and phytopathogenic micro-organisms. Micro-organisms are accountable for any wide selection of fatal illnesses. Scientists worldwide are functioning to develop far more powerful and protected antimicrobial agents to treat ailments triggered by pathogenic organisms. For these causes, the best technique to develop efficient antimicrobial agents should be to synthesize new chemical substances and test their antimicrobial activity. Carbohydrates are important molecules in nature that play several different roles in biological processes. For any extended time, carbohydrates have been an incredibly eye-catching subject for scientists on account of their immense importance in biological systems, such as viral and bacterial infections, cell growth and proliferation, cell ell communication as well as an immune response [1, 2]. Furthermore, they are the source with the metabolic energy provide, along with the fine-tuning of cell ell interactions along with other crucial processes [3, 4]. As outlined by a literature evaluation, many biologically active compounds have aromatic, heteroaromatic, and acyl substituents [52]. For instance, benzene, substituted benzene, nitrogen, sulfur, and halogen-containing substituents are recognized to improve the biological activity on the CB1 site parent compound [136]. It is actually also identified that when an active nucleus is linked to an additional active nucleus, the resulting molecule may have higher biological activity prospective [17, 18]. In addition, selective acylation of carbohydrates and the evaluation of microbia