Product Name :
Anti-CX3CL1, Human antibody
Applications:
ELISA,Flow Cyt
Reactivity :
Human
Conjugate:
Unconjugated
Advantages :
High lot-to-lot consistencyIncreased sensitivity and higher affinityAnimal-free production
Description:
| Description: Anti-CX3CL1, Human antibody is designed for detecting human CX3CL1 specifically. Based on ELISA and/or FCM, Anti-CX3CL1, Human antibody reacts with human CX3CL1 specifically. | Immunogen: Recombinant human CX3CL1 | Host: Alpaca pacous | Isotype: Human IgG1 | Conjugate: Unconjugated | Specificity: Human CX3CL1 | Purity: Recombinant Expression and Affinity purified | Concentration: 1mg/ml | Formation: Liquid, 10mM PBS (pH 7.5), 0.05% sucrose, 0.1% trehalose, 0.01% proclin300, 50% Glycerol | Storage: Store at –20 °C, (Avoid freeze / thaw cycles) | Background:Chemokines are a family of proteins associated with the trafficking of leukocytes in immune surveillance and inflammatory cell recruitment. They are classified based on the positions of key cysteine residues.L82 CX3CL1 is a CX3C chemokine known to induce adhesion and migration of leukocytes mediated by a membrane-bound and soluble form respectively. Recent experiments have shown that CX3CL1 can suppress the production of nitrous oxide, interleukin-6, and TNF-a in activated microglia and neuronal cells, suggesting that it may act as an intrinsic inhibitor against neurotoxicity by activated microglia. Its receptor, CX3CR1, also functions as a co-receptor for HIV-1 and HIV-2 envelope fusion and virus infection, which can be inhibited by CX3CL1.PP1
Description2 :
Anti-CX3CL1, Human antibody is designed for detecting human CX3CL1 specifically.PMID:23789847 Based on ELISA and/or FCM, Anti-CX3CL1, Human antibody reacts with human CX3CL1 specifically.
Immunogen:
Recombinant human CX3CL1
Host :
Alpaca pacous
Isotype:
Human IgG1
Purity :
Recombinant Expression and Affinity purified
Buffer :
Storage :
Store at –20 °C, (Avoid freeze / thaw cycles)
Function:
ELISA: 1:4,000-1:10000Flow Cytometry:1:200-1:1000Dilution factors are presented in the form of a range because the optimal dilution is a function of many factors, such as antigen density, permeability, etc. The actual dilution used must be determined empirically.