Product Name :
IL-21 (mouse), (recombinant)
Sequence:
Purity:
≥95% (SDS-PAGE)
Molecular Weight:
~15.1 kDa
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Appearance:
Use/Stability :
Description:
Interleukin 21 (IL-21) is normally expressed by activated CD4+ T cells.{{362665-56-3} MedChemExpress|{362665-56-3} Purity & Documentation|{362665-56-3} Purity|{362665-56-3} manufacturer} The IL-21 receptor activates the JAK/STAT signaling pathway and is expressed on T, B, and natural killer (NK) cells. IL-21 cooperates with IL-4 for the production of multiple antibody classes in B cells. IL-21 has pleiotropic effects on the proliferation, differentiation, and effector functions of B, T, NK, and dendritic cells.
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Solubility:
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Additional Information :
| Alternative Name Interleukin-21 | Biological Activity Mouse thymocyte proliferation with costimulation; ED50 ≤ 10 ng/mL (≥ 1.{{872573-93-8} site|{872573-93-8} Purity & Documentation|{872573-93-8} Data Sheet|{872573-93-8} manufacturer} 0 x 105 units/mg).PMID:31334979 | Endotoxin Content ≤1 EU/µg protein (LAL test) | Formulation Lyophilized from a sterile (0.2 micron) filtered solution containing 20 mM sodium bicarbonate, pH 8.5. | MW ~15.1 kDa | Purity ≥95% (SDS-PAGE) | Reconstitution Reconstitute in sterile water at 0.1 mg/mL. | Source Produced in E. coli. Contains 130 amino acids. | UniProt ID Q9ES17